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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRAP1
All Species:
13.64
Human Site:
Y64
Identified Species:
30
UniProt:
P42345
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42345
NP_004949.1
2549
288892
Y64
Q
E
E
S
T
R
F
Y
D
Q
L
N
H
H
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535407
2550
288910
Y64
Q
E
E
S
T
R
F
Y
D
Q
L
N
H
H
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLN9
2549
288718
Y64
Q
E
E
S
T
R
F
Y
D
Q
L
N
H
H
I
Rat
Rattus norvegicus
P42346
2549
288776
Y64
Q
E
E
S
T
R
F
Y
D
Q
L
N
H
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510680
2493
282092
A64
T
A
P
R
A
P
G
A
W
L
S
R
R
C
P
Chicken
Gallus gallus
XP_417614
2463
280042
A66
S
K
A
I
G
R
L
A
M
A
G
D
T
F
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070679
2515
286136
V66
E
L
V
S
S
S
D
V
N
E
K
K
G
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VK45
2470
281015
K69
A
T
D
I
N
E
K
K
G
G
A
L
A
M
K
Honey Bee
Apis mellifera
XP_625130
2442
278856
V64
E
M
V
S
G
S
D
V
N
E
K
K
G
G
I
Nematode Worm
Caenorhab. elegans
Q95Q95
2697
306510
I102
A
I
D
G
R
T
D
I
A
S
Q
S
A
I
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32600
2474
281549
L131
F
Q
R
F
S
N
S
L
N
N
K
I
F
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.4
N.A.
98.9
98.9
N.A.
88.8
93.7
N.A.
89.8
N.A.
54
62
34.7
N.A.
Protein Similarity:
100
N.A.
N.A.
99.5
N.A.
99.2
99.2
N.A.
91.2
95.4
N.A.
94.5
N.A.
69.8
75.7
53.4
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
6.6
N.A.
13.3
N.A.
0
13.3
0
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
20
N.A.
40
N.A.
6.6
33.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
58.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
10
0
10
0
0
19
10
10
10
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
19
0
0
0
28
0
37
0
0
10
0
0
0
% D
% Glu:
19
37
37
0
0
10
0
0
0
19
0
0
0
10
0
% E
% Phe:
10
0
0
10
0
0
37
0
0
0
0
0
10
10
0
% F
% Gly:
0
0
0
10
19
0
10
0
10
10
10
0
19
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
37
37
0
% H
% Ile:
0
10
0
19
0
0
0
10
0
0
0
10
0
10
55
% I
% Lys:
0
10
0
0
0
0
10
10
0
0
28
19
0
0
10
% K
% Leu:
0
10
0
0
0
0
10
10
0
10
37
10
0
0
10
% L
% Met:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
10
10
0
0
28
10
0
37
0
0
0
% N
% Pro:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
10
% P
% Gln:
37
10
0
0
0
0
0
0
0
37
10
0
0
0
0
% Q
% Arg:
0
0
10
10
10
46
0
0
0
0
0
10
10
0
0
% R
% Ser:
10
0
0
55
19
19
10
0
0
10
10
10
0
0
0
% S
% Thr:
10
10
0
0
37
10
0
0
0
0
0
0
10
0
10
% T
% Val:
0
0
19
0
0
0
0
19
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
37
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _